Localized Reactions: During or immediately after treatment with lidocaine cream on intact skin, the skin at the site of treatment may develop erythema or edema or may be the locus of abnormal sensation. Tell your doctor if any of these symptoms are severe or do not go away:
For this reason, the patient should avoid inadvertent trauma to the treated area by scratching, rubbing, or exposure to extreme hot or cold temperatures until complete sensation has returned.ĭrug Interactions: Lidocaine cream should be used with caution in patients receiving Class I antiarrhythmic drugs (such as tocainide and mexiletine) since the toxic effects are additive and potentially synergistic.
When lidocaine cream is used, patients should be aware that the production of dermal analgesia may be accompanied by the block of all sensations in the treated skin. Advise patients or caregivers to stop use and seek immediate medical attention if they or someone in their care experience the following signs or symptoms: pale, gray, or blue colored skin (cyanosis) headache rapid heart rate shortness of breath lightheadedness or fatigue. Use of local anesthetics may cause methemoglobinemia, a serious condition that must be treated promptly. Patients with severe hepatic disease, because of their inability to metabolize local anesthetics normally, are at greater risk of developing toxic plasma concentrations of lidocaine. Patients allergic to paraaminobenzoic acid derivatives (procaine, tetracaine, benzocaine, etc.) have not shown cross sensitivity to lidocaine however, lidocaine cream should be used with caution in patients with a history of drug sensitivities, especially if the etiologic agent is uncertain. If eye contact occurs, immediately wash out the eye with water or saline and protect the eye until sensation returns. Lidocaine cream should not be applied to open wounds and kept out of the reach of children.Ĭare should be taken not to allow lidocaine cream to come in contact with the eyes.
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